J Korean Crit Care Nurs Search


Journal of Korean Critical Care Nursing 2016;9(1):40-50.
Published online June 30, 2016.

신생아와 소아의 지속적 신대체요법(CRRT) 적용 특성 및 결과
최앵자, 최수정, 최희정, 유미영
2삼성서울병원 뇌신경센터, 성균관대학교 임상간호대학원
Clinical Differences and Outcomes of Continuous Renal Replacement Therapy between Critically Ill Neonates and Children
Aeng Ja Choi, Su Jung Choi, Hee Jung Choi, Mi Young You
1Intensive Care Unit, Samsung Medical Center
2Brain-Nerve Center, Samsung Medical Center, Graduate School of Clinical Nursing Science, Sungkyunkwan University
3Intensive Care Unit, Samsung Medical Center
4Intensive Care Unit, Samsung Medical Center
Continuous renal replacement therapy (CRRT) has become the preferred dialysis method to support critically ill children and neonates with acute kidney injury. Using CRRT on neonates has increased, but reports about experience are limited. The aim of this study is to describe the clinical application, outcomes, and complications of CRRT in children and neonates.
A retrospective review was performed in 135 children and 36 neonates who underwent CRRT at a tertiary hospital from 2008 to 2015.
At the initiation of CRRT, the median age of children was 72 months and the corrected age of neonates was 37.1 weeks. Median body weight of neonates was 3.2 kg. In neonates, initial degree of fluid overload [FO%], blood flow rate [BFR] and ultrafiltration rate [UFR] rate during CRRT were higher than in children. Median real time of CRRT was 90.5 and 53.5 hours in children and neonates, respectively. Downtime of CRRT was 0.7 and 1.3 hours/day. Median mortality rates (44.4% vs.47.2%) and complication rates were similar between the groups.
CRRT can be used for a wide range of critically ill children and neonates. Different application methods of CRRT can contribute to increased survival of neonates.
Key Words: Critical illness, Child, Neonate, Renal replacement therapy

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